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Anti-LAG-3 & PD-1 Reference An

tibody (Tobemstomig Biosimilar)(BIO0992SM)-100ug/1mg/5mg
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  • ¥2160 - 18900
  • Bioss已认证
  • BIO0992SM
  • 2025年10月10日
  • 产品信息以Bioss网站为准
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    • 规格

      100ug/1mg/5mg

    规格:100ug产品价格:¥2160.0
    规格:1mg产品价格:¥6000.0
    规格:5mg产品价格:¥18900.0
    产品编号BIO0992SM
    英文名称Anti-LAG-3 & PD-1 Reference Antibody (Tobemstomig Biosimilar)
    英文别名LAG3 / CD223 & PDCD1 / PD-1 / CD279; Tobemstomig
    产品应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human
    亚型IgG-like
    性状Lyophilized
    纯化方法Protein A
    克隆类型Monoclonal
    理论分子量145.24 kDa
    储存液100 mM Pro-Ac 20mM Arg pH 5.0
    保存条件-80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions;Avoid repeated freeze-thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

     

    应用推荐稀释比例

     

    产品细节图片1
    The detected weight of Anti-LAG-3 & PD-1 Reference Antibody (Tobemstomig) is 145.01 kDa.
    产品细节图片2
    Anti-LAG-3 & PD-1 Reference Antibody (Tobemstomig)on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
    产品细节图片3
    The purity of Anti-LAG-3 & PD-1 Reference Antibody (Tobemstomig)is 94.61%, determined by SEC-HPLC.
    产品细节图片4
    Tobemstomig bound to LAG-3 protein, and then rebounded to secondary antibodies(Anti-Human-IgG-Fc-HRP) , and read OD450. As shown in fig, Tobemstomig bound human LAG-3 Protein-His, and the EC50 was 0.2401 nM.
    产品细节图片5
    Tobemstomig bound to PD-1 protein, and then rebounded to secondary antibodies(Anti-Human-IgG-Fc-HRP) , and read OD450. As shown in fig, Tobemstomig bound human PD-1 Protein-His, and the EC50 was 0.02504 nM.
    产品细节图片6
    Tobemstomig bound to huPD-1-Jurkat cells, and then rebounded to fluorescent secondary antibodies(Anti-Human IgG, Fcγ PE) , and test by flow cytometry. As shown in fig, Tobemstomig bound to huPD-1-Jurkat cells, and the EC50 was 1.222 nM.
    产品细节图片7
    Tebotelimab bound to huLAG-3-CHO-K cells, and then rebounded to fluorescent secondary antibodies(Anti-Human IgG, Fcγ PE) , and test by flow cytometry. As shown in fig, Tebotelimab bound to huLAG-3-CHO-K cells, and the EC50 was 8.727 nM.

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    图标文献和实验
    相关实验
    • Overview of Biacore Systems and Their Applications

      ., Neumann, M., Tobias, L., Obenauer‐Kutner, L., Jacobs, S., and Cullen, C. 2002. Development of a biosensor‐based method for detection and isotyping of antibody responses to adenoviral‐based gene therapy vectors. Anal. Biochem. 310:107‐113

    • (共享)免疫学专题网址

      . The European CD40L Defect Database. http://www.expasy.ch/cd40lbase/ A database of CD40 ligand defects created by the European Society for Immunodeficiencies. Contains links to Internet resources on X-linked hyper-IgM syndrome. The Fas counterattack

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