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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
None
- 亚型:
IgG
- 保存条件:
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性:
Monoclonal
- 标记物:
FITC Plus Fluorescent Dye
- 适应物种:
mouse
- 保质期:
详见产品包装
- 库存:
充足
- 宿主:
Hamster
- 应用范围:
FC
- 靶点:
CD3e
- 抗体英文名:
FITC Plus Anti-Mouse CD3e (145-2C11)
- 抗体名:
FITC Plus Anti-Mouse CD3e (145-2C11)
- 规格:
25ug/100ug
| 规格: | 25ug | 产品价格: | ¥600.0 |
|---|---|---|---|
| 规格: | 100ug | 产品价格: | ¥1200.0 |
经过测试的应用
| Positive FC detected in | mouse splenocytes |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.5 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
FITC-65060 targets CD3e in FC applications and shows reactivity with mouse samples.
| 经测试应用 | FC |
| 文献引用应用 | FC |
| 经测试反应性 | mouse |
| 文献引用反应性 | mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Hamster / IgG |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | CD3 antigen, epsilon polypeptide |
| 别名 | 145-2C11, AI504783, CD3, CD3epsilon, CD3ε |
| GenBank蛋白编号 | BC098236 |
| 基因名称 | CD3ε |
| Gene ID (NCBI) | 12501 |
| RRID | AB_2883750 |
| 偶联类型 | FITC Plus Fluorescent Dye |
| 最大激发/发射波长 | 495 nm / 524 nm |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | P22646 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).
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文献和实验| Species | Application | Title |
|---|---|---|
| mouse | FC | Adv Sci (Weinh) Cancer-Associated Fibroblast-Induced Remodeling of Tumor Microenvironment in Recurrent Bladder CancerAuthors - Ting Liang |
| mouse | FC | Cell Death Discov TRAF6 triggers Mycobacterium-infected host autophagy through Rab7 ubiquitinationAuthors - Qinmei Ma |
| mouse | FC | Drug Deliv Sonodynamical reversion of immunosuppressive microenvironment in prostate cancer via engineered exosomes.Authors - Dingyi Wang |
| mouse | FC | Asian J Pharm Sci Lignin-assisted construction of sub-10 nm supramolecular self-assembly for photothermal immunotherapy and potentiating anti-PD-1 therapy against primary and distant breast tumorsAuthors - Xudong Fan |
| mouse | FC | J Thromb Haemost Enhanced metabolic activation of and platelet response to clopidogrel in T-cell deficient mice through induction of Cyp2c and Cyp3a and inhibition of Ces1Authors - Li-Ping Jiang |
| mouse | FC | ACS Nano Bioengineered Nanospores Selectively Blocking LC3-Associated Phagocytosis in Tumor-Associated Macrophages Potentiate Antitumor ImmunityAuthors - Yunkai Shang |
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