BAG6 多克隆抗体 26417-1-AP
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BAG6 多克隆抗体 26417-1-AP

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  • ￥1350 - 3000
  • Proteintech已认证
  • 26417-1-AP
  • 2025年10月13日
  • WB, IHC, IF/ICC, IP, ELISA
  • Rabbit
  • human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原：

      Recombinant human BAG6 protein

    • 亚型：

      IgG

    • 保存条件：

      Store at -20°C. Stable for one year after shipment.

    • 克隆性：

      Polyclonal

    • 标记物：

      Unconjugated

    • 适应物种：

      human

    • 保质期：

      详见产品包装

    • 库存：

      充足

    • 宿主：

      Rabbit

    • 应用范围：

      WB, IHC, IF/ICC, IP, ELISA

    • 靶点：

      BAG6

    • 抗体英文名：

      BAG6 Polyclonal antibody

    • 抗体名：

      BAG6 Polyclonal antibody

    • 规格：

      50ul/100ul/150ul

    规格：50ul产品价格：￥1350.0
    规格：100ul产品价格：￥2200.0
    规格：150ul产品价格：￥3000.0

    经过测试的应用

    Positive WB detected inA431 cells, HEK-293 cells, HeLa cells
    Positive IP detected inA431 cells
    Positive IHC detected inhuman breast cancer tissue, human kidney tissue
    Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
    Positive IF/ICC detected inHeLa cells
    Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.

    推荐稀释比

    应用推荐稀释比
    Western Blot (WB)WB : 1:2000-1:16000
    Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
    Immunohistochemistry (IHC)IHC : 1:50-1:500
    Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
    It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    26417-1-AP targets BAG6 in WB, IHC, IF/ICC, IP, CoIP, ELISA applications and shows reactivity with human samples.

    经测试应用 WB, IHC, IF/ICC, IP, ELISA
    文献引用应用WB, IHC, IF, IP, CoIP
    经测试反应性 human
    文献引用反应性human, mouse
    免疫原

    CatNo: Ag24525

    Product name: Recombinant human BAG6 protein

    Source: e coli.-derived, PET30a

    Tag: 6*His

    Domain: 1-184 aa of BC003133

    Sequence: MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRME
    宿主/亚型 Rabbit / IgG
    抗体类别 Polyclonal
    产品类型 Antibody
    全称 HLA-B associated transcript 3
    别名 BAG 6, BAG6, BAT3, D6S52E, G3, HLA B associated transcript 3, Protein G3
    计算分子量 119 kDa
    观测分子量 150 kDa
    GenBank蛋白编号BC003133
    基因名称 BAT3/BAG-6
    Gene ID (NCBI) 7917
    RRIDAB_2880508
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Antigen affinity purification
    UNIPROT IDP46379
    储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
    储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

    背景介绍

    BAT3 also known as Scythe or BAG6, is a nuclear protein implicated in the control of apoptosis and natural killer (NK) cell-dendritic cell (DC) interaction. BAT3 was first discovered as a member of a group of genes located within the class III region of the human major histocompatibility complex on chromosome 6, and has been extensively studied for its role in regulating apoptosis under various stress conditions such as DNA damage and endoplasmic reticulum-related stress. BAT3 has been shown to be required for p53 acetylation, which is critical for the enhancement of p53 transcriptional activity in response to DNA damage. In addition, BAT3 is involved in the regulation of development and reproduction of mammals by acting as a co-chaperone of the heat shock protein HSP70.

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    图标文献和实验
    该产品被引用文献
    SpeciesApplicationTitle
    humanWB

    J Clin Invest

    Chromosomal 3q amplicon encodes essential regulators of secretory vesicles that drive secretory addiction in cancer

    Authors - Xiaochao Tan
    IHC

    Clin Transl Med

    Deubiquitinase USP19 modulates apoptotic calcium release and endoplasmic reticulum stress by deubiquitinating BAG6 in triple negative breast cancer

    Authors - Xiaoqiang Zhang
    humanWB

    EMBO Rep

    UBXN1 maintains ER proteostasis and represses UPR activation by modulating translation

    Authors - Brittany A Ahlstedt
    humanIF

    FASEB J

    BAG6 promotes PINK1 signaling pathway and is essential for mitophagy.

    Authors - Romain Ragimbeau
    humanWB,IP,CoIP,IF

    Mol Cell Biol

    The VCP-UBXN1 complex mediates triage of ubiquitylated cytosolic proteins bound to the BAG6 complex.

    Authors - Rakesh Ganji
    • KD Validated
    humanWB,IF

    Exp Eye Res

    Retinitis pigmentosa 2 pathogenic mutants degrade through BAG6/HUWE1 complex.

    Authors - Jing Zhang
    • KD Validated
    图标技术资料

    暂无技术资料 索取技术资料

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    文献支持
    BAG6 多克隆抗体 26417-1-AP
    ￥1350 - 3000