- ￥1350 - 3000
- Proteintech
- 16268-1-AP
- 2025年10月13日
- WB, IF/ICC, IP, ELISA
- Rabbit
- human, mouse, rat, canine
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human CEP63 protein
- 亚型：
IgG
- 保存条件：
Store at -20°C. Stable for one year after shipment.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
human, mouse, rat, canine
- 保质期：
详见产品包装
- 库存：
充足
- 宿主：
Rabbit
- 应用范围：
WB, IF/ICC, IP, ELISA
- 靶点：
CEP63
- 抗体英文名：
CEP63 Polyclonal antibody
- 抗体名：
CEP63 Polyclonal antibody
- 规格：
50ul/100ul/150ul
| 规格： | 50ul | 产品价格： | ￥1350.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2200.0 |
| 规格： | 150ul | 产品价格： | ￥3000.0 |
经过测试的应用
| Positive WB detected in | HEK-293 cells, mouse liver tissue, HeLa cells, mouse thymus tissue |
| Positive IP detected in | HEK-293 cells |
| Positive IF/ICC detected in | MDCK cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
16268-1-AP targets CEP63 in WB, IF/ICC, IP, ELISA applications and shows reactivity with human, mouse, rat, canine samples.
| 经测试应用 | WB, IF/ICC, IP, ELISA |
| 文献引用应用 | WB, IF, IP |
| 经测试反应性 | human, mouse, rat, canine |
| 文献引用反应性 | human, mouse |
| 免疫原 |
CatNo: Ag9335 Product name: Recombinant human CEP63 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-349 aa of BC014050 Sequence: MEALLEGIQNRGHGGGFLTSCEAELQELMKQIDIMVAHKKSEWEGRTHALETCLKIREQELKSLRSQLDVTHKEVGMLHQQVEEHEKIKQEMTMEYKQELKKLHEELCILKRSYEKLQKKQMREFRGNTKNHREDRSEIERLTAKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELSSQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKLLEALQEEKRELKAALQSQENLIHEARIQKEKLQEKVKATNTQHAVEAISLESVSATCKQLSQELMEKYEELKRMEAHNNEYKAEIKKL |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | centrosomal protein 63kDa |
| 别名 | Centrosomal protein of 63 kDa, centrosomal protein 63kDa |
| 计算分子量 | 703 aa, 81 kDa |
| 观测分子量 | 57-75 kDa |
| GenBank蛋白编号 | BC014050 |
| 基因名称 | CEP63 |
| Gene ID (NCBI) | 80254 |
| RRID | AB_2077079 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q96MT8 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CEP63 is a 63 kDa centrosomal protein. It is required for normal spindle assembly. It maintains centrosome numbers through centrosomal recruitment of CEP152. CEP63 recruits CDK1 to centrosomes. It plays a role in DNA damage response. This antibody can recognize all the four isoforms of CEP63 (56 kDa, 58 kDa, 63 kDa and 81 kDa).
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文献和实验| Species | Application | Title |
|---|---|---|
| mouse | Nat Cell Biol Massive centriole production can occur in the absence of deuterosomes in multiciliated cells.Authors - Olivier Mercey | |
| mouse | WB,IF | Neuron Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate.Authors - Divya Jayaraman |
| human | WB, IF, IP | Dev Cell A dual role for UVRAG in maintaining chromosomal stability independent of autophagy.Authors - Zhen Zhao
|
| mouse | IF | Nat Commun Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis.Authors - Munemasa Mori |
| human | IF | Nat Commun Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites.Authors - Søs Grønbæk Holdgaard |
| human | IF | EMBO J Multimodal mechanisms of human centriole engagement and disengagementAuthors - Kei K Ito |
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