Anti-Hepatitis C Virus antibod

This supplementary information is collated from multiple sources and compiled automatically. Hepatitis C Virus (HCV) is an RNA virus that causes liver infection. It has a small and compact genome of approximately 9.6 kilobases. Structurally HCV contains a single-stranded RNA encased in a nucleocapsid. This virus produces structural proteins like Core E1 and E2 and non-structural proteins such as NS3 NS4A NS4B NS5A and NS5B. These non-structural proteins play key roles in viral replication and assembly. Expression of HCV predominantly occurs in liver hepatocytes where the virus hijacks the host cellular machinery to replicate. Biological function summary Hepatitis C virus engages with host cell pathways to maintain its lifecycle. HCV forms replication complexes within host cells that are critical for its genome replication. These complexes actively interact with lipid metabolism processes which is why the virus associates closely with lipid droplets within hepatocytes. Through this interaction HCV affects host lipid homeostasis a component necessary for viral assembly and release. Since it forms structures that modify the host cell ER membrane understanding the HCV interaction with host cells is fundamental for therapeutic targeting.