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- Bioss
- bs-2443R-BF350
- 2025年10月01日
- 产品信息以Bioss网站为准
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100ul
| 产品编号 | bs-2443R-BF350 |
| 英文名称 | CYP21A2 Rabbit pAb, BF350 conjugated |
| 中文名称 | BF350标记的胆固醇21-羟化酶抗体 |
| 英文别名 | Cytochrome P450 21; cytochrome P450, family 21, subfamily A, polypeptide 2; 21-OH; 21OHA; 21OHB; CA21H; CAH1; CHOLESTEROL 21-HYDROXYLASE; CPS1; CYP21; Cyp21-ps1; Cyp21a1; CYP21A2; Cyp21a2-ps; CYP21B; CYP21OH-A; MGC150536; MGC150537; MGC156449; Oh21-1; Oh21-2; P450C21; P450c21B; CYP21A2; CP21A_HUMAN. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CYP21 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Hormone biosynthesis Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Cytochromes Metabolism > Pathways and Processes > Endocrine metabolism > Hormone biosynthesis Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipases Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism Metabolism > Pathways and Processes > Mitochondrial Metabolism > Cytochromes Signal Transduction > Growth Factors/Hormones > Hormones |
| 亚细胞定位 | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
| 相似性 | Belongs to the cytochrome P450 family. |
| 功能 | Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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