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- Bioss
- bs-1039R-Cy5
- 2025年10月01日
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100ul
| 产品编号 | bs-1039R-Cy5 |
| 英文名称 | Tenascin C Rabbit pAb, Cy5 conjugated |
| 中文名称 | Cy5标记的细胞粘合素(固生蛋白)抗体 |
| 英文别名 | Tn-C; Cytotactin; Glioma associated extracellular matrix antigen; GMEM; GP 150 225; Hexabrachion; HXB; JI; Myotendinous antigen; Neuronectin; Tenascin C; TenascinC; TN; TN C; TNC; TENA_HUMAN. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Tn-C |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Cell Adhesion Proteins > ECM Proteins Neuroscience > Neurology process > Neural Signal Transduction Stem Cells > Mesenchymal Stem Cells > Secreted Molecules Stem Cells > Neural Stem Cells > Extracellular |
| 亚基 | Homohexamer; disulfide-linked. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked within the central globule. Interacts with CSPG4. |
| 亚细胞定位 | Secreted, extracellular space, extracellular matrix. |
| 组织特异性 | Brain specific. |
| 翻译后修饰 | Contains N-linked oligosaccharides, O-linked sialylated structures and O-linked chondroitin sulfate glycosaminoglycans. Contains N-linked oligosaccharides with a sulfated carbohydrate structure (By similarity). O-glycosylated on Thr-36 or Thr-37 with a core 1 or possibly core 8 glycan. |
| 相似性 | Belongs to the tenascin family._x000D_
Contains 15 EGF-like domains._x000D_ Contains 1 fibrinogen C-terminal domain._x000D_ Contains 15 fibronectin type-III domains. |
| 功能 | Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Tenascin, also known as hexabrachion and cytotactin, is an extracellular matrix protein with a spatially and temporally restricted tissue distribution. It is a hexameric, multidomain protein with disulfide linked subunits of 190 to 240 kD, originally characterized as 'myotendinous antigen.' In the embryo it is present in dense mesenchyme surrounding developing epithelia and in developing cartilage and bone. In the adult, tenascin remains present in tendons and myotendinous junctions in the perichondrium and periosteum, as well as in smooth muscle. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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Tenascin C Rabbit pAb, Cy5 conjugated(bs-1039R-Cy5)-100ul
￥2980
