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- Bioss
- bs-3616R-BF647
- 2025年10月01日
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100ul
| 产品编号 | bs-3616R-BF647 |
| 英文名称 | NCF4 Rabbit pAb, BF647 conjugated |
| 中文名称 | BF647标记的嗜中性粒细胞胞浆因子4抗体 |
| 英文别名 | MGC3810; NCF 4; NCF; NCF-4; Ncf4; NCF4_HUMAN; Neutrophil cytosol factor 4; Neutrophil cytosolic factor 4; Neutrophil NADPH oxidase factor 4; p40-phox; p40phox; SH3 and PX domain-containing protein 4. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human NCF4 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies Cell Biology > Other Antibodies > Oxidative Stress Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Mitochondrial |
| 亚基 | p40-PHOX associates primarily with p67-PHOX to form a complex with p47-PHOX. |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Expression is restricted to hematopoietic cells. |
| 相似性 | Contains 1 OPR domain. Contains 1 PX (phox homology) domain. Contains 1 SH3 domain. |
| 功能 | Component of the NADPH-oxidase, a multicomponent enzyme system responsible for the oxidative burst in which electrons are transported from NADPH to molecular oxygen, generating reactive oxidant intermediates. It may be important for the assembly and/or activation of the NADPH-oxidase complex. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | NCF4 is a cytosolic oxidase associated protein. It is a component of the nicotinamide adenine dinucleotide phosphate oxidase, which mediates down regulation of NADPH oxidase through interactions with its SH3 domain. NCF4 is associated with p67 phox but is absent in patients with chronic granulomatous disease who lack p67 phox. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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NCF4 Rabbit pAb, BF647 conjugated(bs-3616R-BF647)-100ul
￥2980
