DPP6 Rabbit pAb, FITC conjugated(bs-9010R-FITC)-100ul

DPP6 Rabbit pAb, FITC conjugat

ed(bs-9010R-FITC)-100ul
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  • ¥2980
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  • bs-9010R-FITC
  • 2025年10月01日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-9010R-FITC
    英文名称DPP6 Rabbit pAb, FITC conjugated
    中文名称FITC标记的二肽基肽酶6抗体
    英文别名Dipeptidyl aminopeptidase like protein 6; Dipeptidyl aminopeptidase related protein; Dipeptidyl peptidase 6; Dipeptidyl peptidase IV like protein; Dipeptidylpeptidase 6; Dipeptidylpeptidase VI; DPPX; DPP6_HUMAN.
    产品应用IF=1:50-200, ICC/IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human DPP6
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Enzymes > Other Enzymes

    亚基Homodimer. Binds KCND2.
    亚细胞定位Membrane; Single-pass type II membrane protein (Probable).
    组织特异性Expressed predominantly in brain.
    相似性Belongs to the peptidase S9B family.
    功能May be involved in the physiological processes of brain function. Has no dipeptidyl aminopeptidase activity. May modulate the cell surface expression and the activity of the potassium channel KCND2. _x000D_
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料DPP6 is a Type-II serine proteinase of the clan SC. The clan SC proteinases have a catalytic triad of Ser-Asp-His, and like other Serine proteinases, the active site serine is in a Gly-Xaa-Ser-Xaa -Gly orientation. DPP6 has an Asp instead of Ser in the catalytic site. DPP6 is a member of a broader family of dipeptidyl peptidases including DPP4, FAP/Seprase, DPP2, DPP8, DPP9, DPP10, which have differing substrate specificity and tissue localizations. The surface-bound DPP6 is a homodimer, and cleavage of in the stalk region releases a shed form of DPP6. The shed is the form found in serum. DPP6 has been found in highest abundance in the brain, but also in the kidney, liver and lung.

     

    应用推荐稀释比例
    {IF}{1:50-200}
    {ICC/IF}{1:100-500}

     

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