SEMA4F Rabbit pAb, FITC conjugated(bs-11478R-FITC)-100ul

SEMA4F Rabbit pAb, FITC conjug

ated(bs-11478R-FITC)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-11478R-FITC
  • 2025年10月01日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-11478R-FITC
    英文名称SEMA4F Rabbit pAb, FITC conjugated
    中文名称FITC标记的跨膜蛋白SEMA4F抗体
    英文别名M SEMA; m Sema M; PRO2353; Sema domain immunoglobulin domain(Ig) transmembrane; Sema M; Sema W; SEMAM; Semaphorin M; Semaphorin W; SEMAW; SEM4F_HUMAN.
    产品应用IF=1:100-500, ICC/IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SEMA4F
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Neurology process > Growth and Development > Axonal Guidance Proteins

    Neuroscience > Sensory System > Visual system

    亚细胞定位Membrane; Single-pass type I membrane protein
    相似性Belongs to the semaphorin family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 PSI domain.
    Contains 1 Sema domain._x000D_
    功能SEMA4F has growth cone collapse activity against retinal ganglion-cell axons.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Semaphorins are a family of cell surface and secreted proteins that are conserved from insects to humans. Members of this family of proteins are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin” domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA4F (semaphorin-4F), also known as SEMAM, SEMAW or PRO2353, is a 770 amino acid member of the semaphorin family. Localized to the membrane, SEMA4F is a single-pass type I protein that is involved in growth cone collapse of retinal ganglion-cell axons. SEMA4F is highly expressed in postnatal brain and lung and contains one immunogloblin-like (Ig-like) domain, one PSI domain and one semaphorin domain. Two isoforms exist due to alternative splicing events.

     

    应用推荐稀释比例
    {IF}{1:100-500}
    {ICC/IF}{1:100-500}

     

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