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- bs-7042R-Cy5
- 2025年09月30日
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100ul
| 产品编号 | bs-7042R-Cy5 |
| 英文名称 | ELF1 Rabbit pAb, Cy5 conjugated |
| 中文名称 | Cy5标记的转录因子ELF1抗体 |
| 英文别名 | mElf 1; E74 like factor 1; ELF 1; ELF1; Ets domain transcription factor; ETS related transcription factor Elf 1; ETS related transcription factor Elf1; p70; Sts1; TRANSCRIPTION FACTOR ELF 1; ELF1_HUMAN. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human ELF1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Ets Epigenetics and Nuclear Signaling > Transcription > Other factors |
| 亚基 | Binds to the underphosphorylated form of RB. May interact with other transcription factors in order to regulate specific genes. Interacts with RUNX1. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Belongs to the ETS family. _x000D_ Contains 1 ETS DNA-binding domain. |
| 功能 | Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | E74 ike Factor 1 is a transcription factor that may be required for the T-cell receptor mediated activation of HIV2 gene expression. It binds to two purine-rich motifs in the HIV-2 enhancer and transcriptionally activates the LYN and mouse BLK promoters. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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ELF1 Rabbit pAb, Cy5 conjugated(bs-7042R-Cy5)-100ul
￥2980
