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- bs-19749R-APC-Cy7
- 2025年09月30日
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100ul
| 产品编号 | bs-19749R-APC-Cy7 |
| 英文名称 | SH3BP2 Rabbit pAb, APC-Cy7 conjugated |
| 中文名称 | APC-Cy7标记的SH3结构域结合蛋白2抗体 |
| 英文别名 | 3BP-2; 3BP2; 3BP2_HUMAN; Abl SH3 binding protein 2; Cherubism; CRBM; CRPM; FLJ42079; FLJ54978; RES4-23; SH3 domain binding protein 2; SH3 domain-binding protein 2; Sh3bp2; TNFAIP3 interacting protein 2. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human SH3BP2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Adapters > Cytoplasmic Signal Transduction > Signaling Pathway > Lipid Signaling |
| 组织特异性 | Expressed in a variety of tissues including lung, liver, skeletal muscle, kidney and pancreas. |
| 翻译后修饰 | Phosphorylated. Phosphorylation at Tyr-448 may stimulate the activity of the LYN kinase (By similarity). |
| 相似性 | Contains 1 PH domain. _x000D_ Contains 1 SH2 domain. |
| 功能 | Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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SH3BP2 Rabbit pAb, APC-Cy7 conjugated(bs-19749R-APC-Cy7)-100ul
￥2980
