TRPC3 Rabbit pAb, Cy3 conjugated(bs-6702R-Cy3)-100ul

TRPC3 Rabbit pAb, Cy3 conjugat

ed(bs-6702R-Cy3)-100ul
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  • ¥2980
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  • bs-6702R-Cy3
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-6702R-Cy3
    英文名称TRPC3 Rabbit pAb, Cy3 conjugated
    中文名称Cy3标记的色氨酸相关蛋白3抗体
    英文别名Htrp 3; Htrp3; MGC124333; Mtrp3; Receptor activated cation channel TRP3v Short transient receptor potential channel 3; Transient receptor potential cation channel subfamily C member 3; Transient receptor potential channel 3; TRANSIENT RECEPTOR POTENTIAL DROSOPHILA HOMOLOG OF 3; Trp related protein 3; TRP3; TrpC3; Trrp3.
    产品应用IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human TRPC3
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cardiovascular > Heart > Hypertrophy

    Cardiovascular > Vasculature > Vasoconstriction

    Neuroscience > Neurology process > Neurogenesis

    Signal Transduction > Signaling Pathway > Calcium Signaling > Calcium Channels

    亚基Interacts with TRPC1, ITPR1, ITPR3, MX1 and RNF24. Interacts with JPH2; the interaction is involved in maintaining Ca(2+) homeostasis in skeletal muscle and is mediated by JPH2 'Ser-165' phosphorylation.
    亚细胞定位Cell Membrane; multi-pass membrane protein
    组织特异性Expressed predominantly in brain and at much lower levels in ovary, colon, small intestine, lung, prostate, placenta and testis.
    相似性Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC3 sub-subfamily.
    Contains 4 ANK repeats.
    功能Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol-1,4,5-triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料TRPC channels form the subfamily of channels in human most closely related to drosophila TRP channels. Structurally, this family shares a number of similar characteristics. At the proximal C-terminus of this sub-family is a TRP box motif containing the invariant EWKFAR sequence and between 3 and 4 ankyrin repeats near the N-terminus. These channels are non-selectively permeable to cations, with a selectivity of calcium over sodium variable among the different members. Many of TRPC channel subunits are able to coassemble.

     

    应用推荐稀释比例
    {IF}{1:100-500}

     

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