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- Bioss
- bs-6510M-BF594
- 2025年09月30日
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100ul
| 产品编号 | bs-6510M-BF594 |
| 英文名称 | ABH8 Mouse pAb, BF594 conjugated |
| 中文名称 | BF594标记的AlkB同源蛋白8抗体 |
| 英文别名 | ABH8; alkB alkylation repair homolog 8(E. coli); alkB alkylation repair homolog 8; AlkB homologue 8; ALKB8_HUMAN; ALKBH8; Alkylated DNA repair protein alkB homolog 8; Probable alpha-ketoglutarate-dependent dioxygenase ABH8; S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8. |
| 产品应用 | ICC/IF=1:50-200, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Mouse |
| 免疫原 | KLH conjugated synthetic peptide derived from human ABH8 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Tumor biomarkers Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing Epigenetics and Nuclear Signaling > DNA / RNA > Translation > tRNAs |
| 亚基 | Interacts with TRMT112._x000D_ |
| 亚细胞定位 | Cytoplasm. Nucleus. Note=Predominantlycytoplasmic._x000D_ |
| 组织特异性 | Widely expressed, with highest expression inspleen, followed by pancreas and lung._x000D_ |
| 相似性 | Belongs to the alkB family._x000D_
Contains 1 Fe2OG dioxygenase domain._x000D_ Contains 1 RRM (RNA recognition motif) domain. |
| 功能 | Catalyzes the methylation of 5-carboxymethyl uridine to5-methylcarboxymethyl uridine at the wobble position of theanticodon loop in tRNA. Catalyzes the last step in the formation of5-methylcarboxymethyl uridine at the wobble position of theanticodon loop in target tRNA. Has a preference for tRNA(Arg) andtRNA(Glu), and does not bind tRNA(Lys). Required for normalsurvival after DNA damage. May inhibit apoptosis and promote cellsurvival and angiogenesis._x000D_ |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis. |
| 应用 | 推荐稀释比例 |
| {ICC/IF} | {1:50-200} |
| {IF} | {1:100-500} |
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ABH8 Mouse pAb, BF594 conjugated(bs-6510M-BF594)-100ul
￥2980
