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- bs-21358R-IRDye800CW
- 2025年09月30日
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100ul
| 产品编号 | bs-21358R-IRDye800CW |
| 英文名称 | P2RX1 Rabbit pAb, IRDye 800CW conjugated |
| 中文名称 | IRDye 800CW标记的三磷酸腺苷受体受体P2X1抗体 |
| 英文别名 | P2X1; ATP receptor; ATP receptor; H sapiens mRNA for ATP receptor; H.sapiens mRNA for ATP receptor; P2 RX1; P2RX1; P2RX1 protein; P2RX1_HUMAN; P2X purinoceptor 1; P2X receptor subunit 1; P2X1; P2X1 receptor; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 1; Purinergic receptor P2X ligand-gated ion channel 1; Purinergic receptor P2X1. |
| 产品应用 | WB=1000-10000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human P2RX1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Vasculature > Vasoconstriction Cardiovascular > Vasculature > Vasodilation Neuroscience > Neurotransmission > Receptors / Channels > Ligand-Gated Ion Channels > P2X Receptors |
| 亚基 | Homo- or heteropolymers (By similarity). _x000D_ |
| 亚细胞定位 | Membrane; Multi-pass membrane protein._x000D_ |
| 相似性 | Belongs to the P2X receptor family. |
| 功能 | Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP. |
| 应用 | 推荐稀释比例 |
| {WB} | {1000-10000} |
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P2RX1 Rabbit pAb, IRDye 800CW conjugated(bs-21358R-IRDye800CW)-100ul
￥2980
