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- bsm-33095M-APC
- 2026年10月17日
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- 技术资料
- 规格：
100ul
| 产品编号 | bsm-33095M-APC |
| 英文名称 | OCT-1 Mouse mAb, APC conjugated |
| 中文名称 | APC标记的胚胎干细胞关键蛋白1单克隆抗体 |
| 英文别名 | class 2; transcription factor 1; FLJ42836; NF A1; NF-A1; Oct1; Oct-1; OCT1; Octamer binding protein 1; Octamer binding transcription factor 1; Octamer-binding protein 1; Octamer-binding transcription factor 1; OTF 1; OTF-1; OTF1; OTTHUMP00000032348; OTTHUMP00000032350; OTTHUMP00000032351; PO21; PO2F1; PO2F1_HUMAN; POU class 2 homeobox 1; POU domain; POU domain class 2 transcription factor 1; POU2F1. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Mouse |
| 免疫原 | KLH conjugated synthetic peptide derived from human Oct1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families > OCT |
| 亚基 | Interacts with NR3C1, AR, PGR and HCFC1. Associates with the herpes simplex virus VP16-induced complex; binding to HCFC1 activates the viral transcriptional activator VP16 for association with POU2F1, to form a multiprotein-DNA complex responsible for activating transcription of the viral immediate early genes. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Ubiquitous. Isoform 2 is lymphocyte-specific. |
| 翻译后修饰 | Phosphorylated by PRKDC. |
| 相似性 | Belongs to the POU transcription factor family. Class-2 subfamily. Contains 1 homeobox DNA-binding domain._x000D_ Contains 1 POU-specific domain._x000D_ |
| 功能 | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Oct1 is a transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. It modulates transcription transactivation by NR3C1, AR and PGR and interacts with NR3C1, AR and PGR. Oct1 is Ubiquitous and belongs to the POU transcription factor family class 2 subfamily. Oct1 contains 1 homeobox domain. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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POU2F1 | Oct-1 Mouse mAb, APC conj.(bsm-33095M-APC)-100ul
￥2980
