- ￥2980
- Bioss
- bs-10581R-RBITC
- 2026年10月17日
企业认证
相关产品推荐更多 >
FBXO10 | FBX10 Rabbit pAb, PE-Cy5.5 conj.(bs-16045R-PE-Cy5.5)-100ul
￥2980
MET | c-Met/HGFR (p-Y1234/Y1235) Rabbit pAb, APC-Cy7 conj.(bs-3272R-APC-Cy7)-100ul
￥2980
PRKCD | PKC delta Rabbit pAb, BF555 conj.(bs-23441R-BF555)-100ul
￥2980
DRD1 Rabbit pAb, BF594 conj.(bs-1007R-BF594)-100ul
￥2980
C4BPA Rabbit pAb, APC-Cy5.5 conj.(bs-15185R-APC-Cy5.5)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
相关阅读
源叶生物 十万种现货试剂速发，品质稳、品类全，实验不再等！Takara 秋促来袭，提取+反转录+定量套装仅 1200 元abinScience 体内级抗体 全年锁价 低至 ￥1200阿拉丁 22万+ 科研级产品现货速发，品质严控、科研无忧- 详细信息
- 技术资料
- 规格：
100ul
| 产品编号 | bs-10581R-RBITC |
| 英文名称 | MMP13 Rabbit pAb, RBITC conjugated |
| 中文名称 | RBITC标记的基质金属蛋白酶13抗体 |
| 英文别名 | CLG 3; CLG3; Collagenase 3; Collagenase3; MMP13; MMP 13; MMP-13; Matrix Metalloproteinase 13; MMP 13; MMP13_HUMAN. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MMP13 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Invasion/microenvironment > Angiogenesis > ECM enzymes > MMPs Cancer > Invasion/microenvironment > ECM > Extracellular matrix > MMPs Cancer > Tumor biomarkers > Enzymes > MMPs Cardiovascular > Angiogenesis > Adhesion / ECM > Matrix Metalloproteinases > MMP Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Metalloprotease > MMPs Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > Tumor biomarkers ELISA kits Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Enzymes > MMP |
| 亚细胞定位 | Secreted, extracellular space, extracellular matrix (Probable). |
| 组织特异性 | Seems to be specific to breast carcinomas. |
| 翻译后修饰 | Defects in MMP13 are the cause of spondyloepimetaphyseal dysplasia Missouri type (SEMD-MO) [MIM:602111]. A bone disease characterized by moderate to severe metaphyseal changes, mild epiphyseal involvement, rhizomelic shortening of the lower limbs with bowing of the femora and/or tibiae, coxa vara, genu varum and pear-shaped vertebrae in childhood. Epimetaphyseal changes improve with age._x000D_
Defects in MMP13 are the cause of metaphyseal anadysplasia type 1 (MANDP1) [MIM:602111]. Metaphyseal anadysplasia consists of an abnormal bone development characterized by severe skeletal changes that, in contrast with the progressive course of most other skeletal dysplasias, resolve spontaneously with age. Clinical characteristics are evident from the first months of life and include slight shortness of stature and a mild varus deformity of the legs. Patients attain a normal stature in adolescence and show improvement or complete resolution of varus deformity of the legs and rhizomelic micromelia. |
| 相似性 | Belongs to the peptidase M10A family. _x000D_ Contains 4 hemopexin-like domains. |
| 功能 | Degrades collagen type I. Does not act on gelatin or casein. Could have a role in tumoral process. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | bs-0575P is one synthetic peptide derived from human MMP13. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
