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- Bioss
- bs-7850R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-7850R-AP |
| 英文名称 | TTK Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的单极纺锤体蛋白激酶1抗体 |
| 英文别名 | Dual specificity protein kinase TTK; ECSTY kinase; ESK; FLJ38280; hMPS1; Monopolar Spindle 1 Like 1; Mps 1; Mps-1; MPS1L1; phosphotyrosine Picked Threonine Kinase; PYT; MPS1; TTK Protein Kinase; TTK_HUMAN. |
| 产品应用 | ELISA=1:500-5000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human TTK |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Cell Cycle > Cell Division > Spindle Cell Biology > Cell Cycle > Kinases/Phosphatases Epigenetics and Nuclear Signaling > Cell cycle > Kinases/Phosphatases |
| 组织特异性 | Present in rapidly proliferating cell lines. |
| 相似性 | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 1 protein kinase domain. |
| 功能 | Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Mps1 (TTK) is a tyrosine and serine/threonine dual-specificity kinase required for centrosome duplication and the spindle checkpoint and has recently been shown to have a role in centrosome duplication. Alterations to Mps1 have been associated with cell transformation and chromosome instability in different tumor models. It is present in rapidly proliferating cell lines. |
| 应用 | 推荐稀释比例 |
| {ELISA} | {1:500-5000} |
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TTK Rabbit pAb, AP conjugated(bs-7850R-AP)-100ul
￥2980
