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- bs-7672R-APC-Cy5.5
- 2025年09月30日
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100ul
| 产品编号 | bs-7672R-APC-Cy5.5 |
| 英文名称 | NRH2 Rabbit pAb, APC-Cy5.5 conjugated |
| 中文名称 | APC-Cy5.5标记的死亡结构域蛋白NRH2抗体 |
| 英文别名 | NRADD; PLAIDD; NRADD_RAT; Death domain-containing membrane protein NRADD; Neurotrophin receptor homolog-2; Neurotrophin receptor-alike death domain protein; P75-like apoptosis-inducing death domain protein. |
| 中文别名 | 神经营养因子受体相似的死亡结构域蛋白; |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from rat NRH2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Interacts with NTRK1. Isoform 1 andisoform 2 interact with NGFR. Interacts with SORT1._x000D_ |
| 亚细胞定位 | Cell membrane; Single-pass type III membraneprotein. Nucleus (By similarity). Note=Proteolytic processing givesrise to an intracellular domain that translocates to the nucleus. |
| 组织特异性 | Detected in embryo, including embryonic brain.Detected at very low levels in adult testis, spleen, thymus andlung._x000D_ |
| 翻译后修饰 | Isoform 1 is N-glycosylated. Isoform 2 is not N-glycosylated._x000D_ |
| 相似性 | Contains 1 death domain._x000D_ |
| 功能 | Modulates NTRK1 signaling. Can activate severalintracellular signaling pathways, leading to activation of JUN.Promotes translocation of SORT1 to the cell membrane, and therebyhinders lysosomal degradation of SOTR1 and promotes its interactionwith NGFR (By similarity). Both isoform 1 and isoform 2 promoteapoptosis. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | A single transmembrane protein highly expressed in embryonic tissues and involved in inducing apoptosis. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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NRH2 Rabbit pAb, APC-Cy5.5 conjugated(bs-7672R-APC-Cy5.5)-100ul
￥2980
