DIAPH2 Rabbit pAb, BF594 conjugated(bs-13002R-BF594)-100ul

DIAPH2 Rabbit pAb, BF594 conju

gated(bs-13002R-BF594)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-13002R-BF594
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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    • 规格：

      100ul

    产品编号bs-13002R-BF594
    英文名称DIAPH2 Rabbit pAb, BF594 conjugated
    中文名称BF594标记的DIAPH2蛋白抗体
    英文别名Dia 2; DIA; Dia drome; Dia2; Diap 2; Diap2; DIAP2_HUMAN; DIAPH 2; DIAPH2; Diaphanous 2; Diaphanous homolog 2(Drosophila); Diaphanous homolog 2; Diaphanous related formin 2; Diaphanous-related formin-2; Diaphanous2; Diaphorase 2; Diaphorase2; DRF 2; DRF2; FLJ11167; OTTHUMP00000024270; OTTHUMP00000024271; OTTHUMP00000062171; POF 2; POF; POF2; Protein diaphanous homolog 2.
    产品应用IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human DIAPH2/Dia2
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin Binding Proteins

    Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation

    亚基Isoform 3 interacts with RHOD in the GTP-bound form.
    亚细胞定位Cytoplasm > cytosol. Early endosome. Isoform 3 is cytosolic but when coexpressed with RHOD, the 2 proteins colocalize to early endosomes.
    组织特异性Expressed in testis, ovary, small intestine, prostate, lung, liver, kidney and leukocytes.
    相似性Belongs to the formin homology family. Diaphanous subfamily.
    _x000D_ Contains 1 DAD (diaphanous autoregulatory) domain.
    _x000D_ Contains 1 FH1 (formin homology 1) domain.
    _x000D_ Contains 1 FH2 (formin homology 2) domain.
    _x000D_ Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain.
    功能Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料The product of this gene belongs to the diaphanous subfamily of the formin homology family of proteins. This gene may play a role in the development and normal function of the ovaries. Defects in this gene have been linked to premature ovarian failure 2. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {IF}{1:100-500}

     

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