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- Bioss
- bs-12996R-BF647
- 2025年09月30日
- 产品信息以Bioss网站为准
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100ul
| 产品编号 | bs-12996R-BF647 |
| 英文名称 | Dermcidin Rabbit pAb, BF647 conjugated |
| 中文名称 | BF647标记的抗菌蛋白DCD抗体 |
| 英文别名 | AIDD; DCD 1; dcd; DCD-1; DCD_HUMAN; DSEP; HCAP; PIF; Preproteolysin; Dermcidin. |
| 产品应用 | ICC/IF=1:50-200, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Dermcidin/DCD |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Specifically and constitutively expressed in eccrine sweat gland cells. Secreted into the sweat at a concentration of 1-10 micrograms/ml. |
| 功能 | DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. _x000D_ Survival-promoting peptide promotes survival of neurons and displays phosphatase activity. It may bind IgG. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Antimicrobial peptides participate in the innate response, which may provide a barrier for protection against infection. The Dermcidin gene encodes an antimicrobial peptide DCD-1, which is constitutively expressed in sweat glands, secreted into the sweat, and transported to the epidermal surface. DCD-1 displays antimicrobial activity in response to a variety of pathogenic microorganisms. Overexpression of Dermcidin in breast cancers promotes cell growth and survival, and is coupled with a focal copy number gain of its locus on human chromosome 12q13.2. |
| 应用 | 推荐稀释比例 |
| {ICC/IF} | {1:50-200} |
| {IF} | {1:100-500} |
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Dermcidin Rabbit pAb, BF647 conjugated(bs-12996R-BF647)-100ul
￥2980
