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- bs-12991R-APC
- 2025年09月30日
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100ul
| 产品编号 | bs-12991R-APC |
| 英文名称 | phospho-delta 1 Catenin (Thr916) Rabbit pAb, APC conjugated |
| 中文名称 | APC标记的磷酸化δ连环蛋白抗体 |
| 英文别名 | delta 1 Catenin(phospho T916); p-delta 1 Catenin(phospho T916); Cadherin associated Src substrate; Cadherin-associated Src substrate; CAS; Catenin(cadherin associated protein) delta 1; Catenin delta 1; Catenin delta-1; CTND1_HUMAN; CTNND 1; CTNND; CTNND1; KIAA0384; p120; P120 CAS; p120 catenin; P120 CTN; p120(cas); p120(ctn); P120CAS; P120CTN. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthesised phosphopeptide derived from human delta 1 Catenin around the phosphorylation site of Thr916 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Catenins Stem Cells > Signaling Pathways > Wnt > Cytoplasmic |
| 亚基 | Cytoplasm. Nucleus. Cell membrane. Note=Interaction with GLIS2 promotes nuclear translocation. Detected at cell-cell contacts. NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm. |
| 亚细胞定位 | Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm. |
| 组织特异性 | Expressed in vascular endothelium. |
| 翻译后修饰 | Phosphorylated by FER and other protein-tyrosine kinases. Phosphorylated at Ser-288 by PAK7/PAK5. Dephosphorylated by PTPRJ. |
| 相似性 | Belongs to the beta-catenin family. Contains 10 ARM repeats. |
| 功能 | Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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phospho-delta 1 Catenin (Thr916) Rabbit pAb, APC conjugated(bs-12991R-APC)-100ul
￥2980
