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- Bioss
- bs-6681R-BF405
- 2025年09月30日
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100ul
| 产品编号 | bs-6681R-BF405 |
| 英文名称 | BNIP1 Rabbit pAb, BF405 conjugated |
| 中文名称 | BF405标记的囊泡转运蛋白SEC20 抗体 |
| 英文别名 | NIP1; BCL2 adenovirus E1B 19kD interacting protein 1; BCL2/adenovirus E1B 19 kDa protein-interacting protein 1; BNIP1; sec20; SEC20_HUMAN; SEC20L; Transformation-related gene 8 protein; TRG-8; TRG8; Vesicle transport protein SEC20. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human BNIP1/TRG8 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Apoptosis > Intracellular > Bcl2 Family Neuroscience > Neurotransmission > Secretory Vesicles > SNAPs & SNAREs Signal Transduction > Protein Trafficking > Vesicle Transport > SNAPs & SNAREs |
| 亚基 | Component of a SNARE complex consisting of STX18, USE1L, BNIP1/SEC20L and SEC22B. Interacts directly with STX18, RINT1/TIP20L and NAPA. Interacts with ZW10 through RINT1. Interacts with BCL2 and adenovirus E1B 19 kDa protein._x000D_ |
| 亚细胞定位 | Mitochondrion. Endoplasmic reticulum membrane; Single-pass type IV membrane protein._x000D_ |
| 组织特异性 | Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine._x000D_ |
| 翻译后修饰 | 'Lys-63'-linked polyubiquitination by RNF185 allows recruiting of autophagy receptor SQSTM1, which simultaneously binds both ubiquitin and LC3 to link ubiquitination and autophagy._x000D_ |
| 相似性 | Belongs to the SEC20 family. |
| 功能 | SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death.Tissue specificity: Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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BNIP1 Rabbit pAb, BF405 conjugated(bs-6681R-BF405)-100ul
￥2980
