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- bs-10485R-PacificBlue
- 2025年09月30日
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100ul
| 产品编号 | bs-10485R-PacificBlue |
| 英文名称 | Heparanase 2/HPSE2 Rabbit pAb, Pacific Blue conjugated |
| 中文名称 | Pacific Blue标记的乙酰肝素酶2抗体 |
| 英文别名 | heparanase 2; heparanase 3; Heparanase-2; Heparanase 2; heparanase-like protein; Hpa2; HPR2; HPSE2; HPSE2_HUMAN; UFS; Inactive heparanase-2. |
| 产品应用 | ICC/IF=1:50-200, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Heparanase 2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Interacts with HPSE. Interacts with SDC1 (via glycan chains). |
| 亚细胞定位 | Secreted, extracellular space, extracellular matrix. |
| 组织特异性 | Widely expressed, with the highest expression in brain, mammary gland, prostate, small intestine, testis and uterus. In the central nervous system, expressed in the spinal chord, caudate nucleus, thalamus, substantia nigra, medulla oblongata, putamen and pons. In the urinary bladder, expressed in longitudinal and circular layers of detrusor muscle. Found both in normal and cancer tissues. |
| 相似性 | Belongs to the glycosyl hydrolase 79 family. |
| 功能 | Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro). |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]. |
| 应用 | 推荐稀释比例 |
| {ICC/IF} | {1:50-200} |
| {IF} | {1:100-500} |
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Heparanase 2/HPSE2 Rabbit pAb, Pacific Blue conjugated(bs-10485R-PacificBlue)-100ul
￥2980
