GRF2 Rabbit pAb, IRDye 800CW conjugated(bs-16311R-IRDye800CW)-100ul

GRF2 Rabbit pAb, IRDye 800CW c

onjugated(bs-16311R-IRDye800CW)-100ul
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  • ¥2980
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  • bs-16311R-IRDye800CW
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-16311R-IRDye800CW
    英文名称GRF2 Rabbit pAb, IRDye 800CW conjugated
    中文名称IRDye 800CW标记的G蛋白偶联受体释放因子2抗体
    英文别名C3G; C3G protein; CRK SH3 binding GNRP; CRK SH3-binding GNRP; DKFZp781P1719; GRF 2; GRF2; Guanine nucleotide releasing factor 2(specific for crk proto oncogene); Guanine nucleotide releasing factor 2; Guanine nucleotide-releasing factor 2; OTTHUMP00000064558; Protein C3G; Rap guanine nucleotide exchange factor(GEF) 1; Rap guanine nucleotide exchange factor 1; RAPGEF 1; RAPGEF1; RPGF1_HUMAN.
    产品应用WB=1000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human GRF2
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Ras Family

    Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Regulators

    组织特异性Ubiquitously expressed in adult and fetus. Expression is high in adult skeletal muscle and placenta and in fetal brain and heart. Low levels of expression in adult and fetal liver.
    相似性Contains 1 N-terminal Ras-GEF domain.
    _x000D_ Contains 1 Ras-GEF domain.
    功能Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {WB}{1000-10000}

     

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