MID2 Rabbit pAb, Pacific Blue conjugated(bs-11029R-PacificBlue)-100ul

MID2 Rabbit pAb, Pacific Blue

conjugated(bs-11029R-PacificBlue)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-11029R-PacificBlue
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-11029R-PacificBlue
    英文名称MID2 Rabbit pAb, Pacific Blue conjugated
    中文名称Pacific Blue标记的环指蛋白60抗体
    英文别名FXY2; MID2; Midin-2; Midline 2; Midline defect 2; Midline-2; Probable E3 ubiquitin-protein ligase MID2; RING finger protein 60; Ring finger protein protein 60; RNF60; TRIM1; TRIM1_HUMAN; Tripartite motif protein 1; Tripartite motif-containing protein 1; Tripartite motif-containing protein 1; Midline defect 2; FLJ37715; FLJ41813.
    产品应用ICC/IF=1:50-200, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Midline-2
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > Cell cycle > Ubiquitin ligases

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger

    Neuroscience > Cell Adhesion Proteins > Cytoskeletal Proteins > Microtubules

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microtubules > MT Associated Proteins > MAP

    亚基Homodimer or heterodimer with MID1. Interacts with IGBP1.
    组织特异性Low level in fetal kidney and lung, and in adult prostate, ovary and small intestine.
    翻译后修饰Phosphorylated on serine and threonine residues.
    相似性Belongs to the TRIM/RBCC family._x000D_
    Contains 2 B box-type zinc fingers._x000D_
    Contains 1 B30.2/SPRY domain._x000D_
    Contains 1 COS domain._x000D_
    Contains 1 fibronectin type-III domain._x000D_
    Contains 1 RING-type zinc finger.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料Midline-2 is a 715 amino acid protein encoded by the human gene MID2. Midline-2 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, one B30.2/SPRY domain, one COS domain, one fibronectin type-III domain and one RING-type zinc finger. Midline-2 is a cytoplasmic protein found as a homodimer or heterodimer with Midline-1. It also interacts with IGBP1 (Lymphocyte signaling protein A4). Dimerization is mediated by the tripartite motif (RBCC; RING- and B box-type zinc fingers and coiled coil domains) and microtubule association is dependent on the C-terminal B30.2 domain. Midline-2 is expressed at low levels in fetal kidney and lung, and in adult prostate, ovary and small intestine.

     

    应用推荐稀释比例
    {ICC/IF}{1:50-200}
    {IF}{1:100-500}

     

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