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- Bioss
- bs-14502R-BF680
- 2025年09月30日
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100ul
| 产品编号 | bs-14502R-BF680 |
| 英文名称 | EDEM3 Rabbit pAb, BF680 conjugated |
| 中文名称 | BF680标记的EDEM3蛋白抗体 |
| 英文别名 | C1orf22; EDEM 3; edem3; EDEM3_HUMAN; ER degradation enhancer, mannosidase alpha like 3; ER degradation enhancing alpha mannosidase like 3; ER degradation enhancing alpha mannosidase like 3; ER degradation-enhancing alpha-mannosidase-like 3. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human EDEM3 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Protein Trafficking > ER Proteins |
| 亚细胞定位 | Endoplasmic reticulum lumen. |
| 相似性 | Belongs to the glycosyl hydrolase 47 family. _x000D_ Contains 1 PA (protease associated) domain. |
| 功能 | Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes. This process depends on mannose-trimming from the N-glycans. Seems to have alpha 1,2-mannosidase activity. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM, Mar 2008] |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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EDEM3 Rabbit pAb, BF680 conjugated(bs-14502R-BF680)-100ul
￥2980
