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- Bioss
- bs-18980R-BF405
- 2025年09月30日
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100ul
| 产品编号 | bs-18980R-BF405 |
| 英文名称 | N ras + c Ha ras Rabbit pAb, BF405 conjugated |
| 中文名称 | BF405标记的HRAS1抗体 |
| 英文别名 | ALPS4; GTPase HRas; GTPase NRas; HRAS1; N ras protein part 4; Neuroblastoma RAS viral(v-ras) oncogene homolog; NRAS; Ras family small GTP binding protein H Ras; RAS1; Transforming protein p21. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human N ras + c Ha ras |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Oncoproteins/suppressors > Oncoproteins > Signal transducers Cancer > Signal transduction > G protein signaling > Small G proteins > Ras family Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Ras Family |
| 亚基 | Interacts (active GTP-bound form preferentially) with RGS14. Interacts (active GTP-bound form) with RASSF7. |
| 亚细胞定位 | Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor. Note=Shuttles between the plasma membrane and the Golgi apparatus. |
| 组织特异性 | Widely expressed. |
| 翻译后修饰 | Palmitoylated by the ZDHHC9-GOLGA7 complex. A continuous cycle of de- and re-palmitoylation regulates rapid exchange between plasma membrane and Golgi. Acetylation at Lys-104 prevents interaction with guanine nucleotide exchange factors (GEFs). |
| 相似性 | Belongs to the small GTPase superfamily. Ras family. |
| 功能 | Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | N-RAS (neuroblastoma RAS viral oncogene homolog) analogously to other GTP-binding proteins (such as Translation Elongation Factor EFTu or signal transducing G-Proteins) RAS proteins are involved in signal transduction pathways, ras gene family is part of the ras superfamily including the mammalian RAS, RAL, RAC, RHO, RAP, and RAB gene families and the yeast homologs like SEC4 and YPT1 genes; genes encode small monomeric proteins of low molecular mass (20-30 kDa) which share at least 30% homology to RAS proteins. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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N ras + c Ha ras Rabbit pAb, BF405 conjugated(bs-18980R-BF405)-100ul
￥2980
