PCDH10 Rabbit pAb, PE-Cy5.5 conjugated(bs-13723R-PE-Cy5.5)-100ul

PCDH10 Rabbit pAb, PE-Cy5.5 co

njugated(bs-13723R-PE-Cy5.5)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-13723R-PE-Cy5.5
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-13723R-PE-Cy5.5
    英文名称PCDH10 Rabbit pAb, PE-Cy5.5 conjugated
    中文名称PE-Cy5.5标记的原钙粘附蛋白10抗体
    英文别名DKFZp761O2023; KIAA1400; MGC133344; OL PCDH; Ortholog of OL pcdh; OTTHUMP00000220001; PCD10_HUMAN; PCDH10; PCDH19; Protocadherin 10; Protocadherin-10.
    产品应用IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human PCDH10
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cadherins

    亚细胞定位Cell membrane.
    组织特异性Moderately expressed in all regions of the brain examined, as well as in testis and ovary, and low expression in all other tissues tested.
    相似性Contains 6 cadherin domains.
    功能Potential calcium-dependent cell-adhesion protein.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH10 (protocadherin 10), also known as PCDH19 or OL-PCDH, is a 1,040 amino acid single-pass type I membrane protein that contains six cadherin domains and one transmembrane domain. Expressed at moderate levels in brain, ovary and testis and present at lower levels in all other tissues, PCDH10 functions as a calcium-dependent cell-adhesion protein that may function as a tumor suppressor. When underexpressed, PCDH10 is associated with the progression of various carcinomas, including gastric cancer.

     

    应用推荐稀释比例
    {IF}{1:100-500}

     

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