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- bs-19784R-PacificBlue
- 2025年09月30日
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100ul
| 产品编号 | bs-19784R-PacificBlue |
| 英文名称 | RECQ1 Rabbit pAb, Pacific Blue conjugated |
| 中文名称 | Pacific Blue标记的DNA解旋酶Q1样抗体 |
| 英文别名 | ATP dependent DNA helicase Q1; DNA helicase Q1 like; DNA helicase RecQ like type 1; RECQ L1; RecQ protein like 1; RecQ protein like; RECQL; RECQL1. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human RECQ1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > DNA Damage & Repair > Mismatch Repair Epigenetics and Nuclear Signaling > DNA / RNA > DNA Damage & Repair > Nucl. Excision Repair |
| 亚基 | Interacts with EXO1 and MLH1. |
| 亚细胞定位 | Nuclear |
| 组织特异性 | High expression in heart, lung, skeletal muscle and kidney, low expression in brain. |
| 相似性 | Belongs to the helicase family. RecQ subfamily _x000D_ Contains 1 helicase ATP-binding domain _x000D_ Contains 1 helicase C-terminal domain. |
| 功能 | DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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RECQ1 Rabbit pAb, Pacific Blue conjugated(bs-19784R-PacificBlue)-100ul
￥2980
