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- bs-5736R-Cy5
- 2025年09月30日
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100ul
| 产品编号 | bs-5736R-Cy5 |
| 英文名称 | TACC2 Rabbit pAb, Cy5 conjugated |
| 中文名称 | Cy5标记的转化酸性卷曲含蛋白质2 |
| 英文别名 | TACC2_HUMAN; Anti zuai 1; AZU 1; AZU1; ECTACC; TACC 2; Transforming acidic coiled coil containing protein 2. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human TACC2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cell cycle > Cell division Cell Biology > Cell Cycle > Cell Division > Centromere Tags & Cell Markers > Subcellular Markers > Organelles > Centrosome |
| 亚基 | Interacts with CCDC100/CEP120 (By similarity). Interacts with microtubules. Interacts with YEATS4, GCN5L2 and PCAF. |
| 亚细胞定位 | Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, centrosome. |
| 组织特异性 | Strongly expressed in heart, skeletal muscle, brain, prostate, thyroid and trachea. |
| 翻译后修饰 | Phosphorylated by TTK; which is required for localization in centrosome. |
| 相似性 | Belongs to the TACC family. Contains 1 SPAZ (Ser/Pro-rich AZU-1) domain. |
| 功能 | Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | TACC2 is a conserved family of centrosome and microtubule interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is thought to affect the progression of breast tumors. Expression of this gene is also induced by erythropoietin. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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TACC2 Rabbit pAb, Cy5 conjugated(bs-5736R-Cy5)-100ul
￥2980
