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- bs-14494R-PerCP
- 2025年09月30日
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100ul
| 产品编号 | bs-14494R-PerCP |
| 英文名称 | EBNA 3C Rabbit pAb, PerCP conjugated |
| 中文名称 | PerCP标记的EB病毒核抗原-3C抗体 |
| 英文别名 | EBNA3C; EBNA 4B; EBNA 6; EBNA 3C; EBNA6_EBVB9; EBV; EBV nuclear antigen 6; Epstein Barr nuclear antigen 6; HHV4; Human Herpesvirus 4. |
| 产品应用 | ICC/IF=1:50-200, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human EBNA 3C |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Microbiology > Organism > Virus > DNA Virus > double stranded DNA Virus > EBNA |
| 亚基 | Interacts with host CTPB1; this interaction seems mportant for EBNA6-mediated transcriptional repression. Interacts ith host MYC; this interaction enhances MYC stability. Interacts via N-terminus) with host RBPJ. |
| 亚细胞定位 | Host nucleus matrix. Note=Associated with he nuclear matrix. |
| 相似性 | Belongs to the herpesviridae EBNA-6 family. |
| 功能 | Plays an essential role for the activation and mmortalization of human B-cells. Represses transcription of viral romoters TP1 and Cp through interaction with host RBPJ, and nhibits EBNA2-mediated activation of these promoters. Since Cp is he promoter for all EBNA mRNAs, EBNA6 probably contributes to a egative autoregulatory control loop. Alternatively, EBNA6 also egulates the transcription of the EBV oncogene LMP1 in a cell ycle-dependent manner. It modulates the activity of several host roteins involved in cell cycle regulation including host cyclin A, YC, RB and p27 mainly through binding to the host SCF(SKP2) omplex. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | EBNA 3C is a latent viral nuclear protein expressed in EBV transformed lymphoblastic cell lines and is essential for EBV mediated transformation of these cell lines. This viral nuclear protein is essential for EBV mediated positive immunoblastic lymphomas, and functions as a transcription factor. |
| 应用 | 推荐稀释比例 |
| {ICC/IF} | {1:50-200} |
| {IF} | {1:100-500} |
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EBNA 3C Rabbit pAb, PerCP conjugated(bs-14494R-PerCP)-100ul
￥2980
