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- Bioss
- bs-4782R-APC
- 2025年09月30日
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100ul
| 产品编号 | bs-4782R-APC |
| 英文名称 | HSPB2 Rabbit pAb, APC conjugated |
| 中文名称 | APC标记的热休克蛋白B2抗体 |
| 英文别名 | DMPK-binding protein; Heat shock 27kD protein 2; Heat shock 27kDa protein 2; Heat shock protein beta-2; Heat-shock protein beta-2; Hs.78846; HSP27; HspB2; HSPB2_HUMAN; LOH11CR1K; MGC133245; MKBP. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human HSPB2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Protein Trafficking > Chaperones > Heat Shock Proteins Signal Transduction > Protein Trafficking > Chaperones > Other Chaperones |
| 亚基 | Interacts with DMPK; may enhance its kinase activity. |
| 亚细胞定位 | Cytoplasm. Nucleus. Localizes to nuclear foci. |
| 组织特异性 | Expressed preferentially in skeletal muscle and heart. |
| 相似性 | Belongs to the small heat shock protein (HSP20) family. |
| 功能 | May regulate the kinase DMPK. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. HSPB2 (heat shock 27 kDa protein 2), also known as HSP 27 or MKBP, is a 182 amino acid protein that belongs to the heat shock protein family and is expressed preferentially in heart and skeletal muscle. Localized to mitochondria, HSPB2 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also interact with the Actin cytoskeleton and prevent apoptotic cell death. HSPB2 is abundantly expressed in several cancer cell lines, suggesting that HSPB2 may be an important factor in tumor transformation and metastasis. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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HSPB2 Rabbit pAb, APC conjugated(bs-4782R-APC)-100ul
￥2980
