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- bs-5158R-Cy3
- 2025年09月30日
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100ul
| 产品编号 | bs-5158R-Cy3 |
| 英文名称 | Cystatin B Rabbit pAb, Cy3 conjugated |
| 中文名称 | Cy3标记的胱抑素B/半胱氨酸蛋白酶抑制剂B抗体 |
| 英文别名 | CPI B; CPI-B; CST6; CSTB; Cystatin B; Cystatin-B; CYTB; EPM1; Liver thiol proteinase inhibitor; PME; STFB; CHROW21; CYTB_HUMAN; EPM1A; Stefin-B; ULD. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Cystatin B |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Protease inhibitors Cell Biology > Proteolysis / Ubiquitin > Protease inhibitors > Other protease inhibitors |
| 亚细胞定位 | Cytoplasm. Nucleus.Secreted. |
| 组织特异性 | Restricted to the stratum granulosum of normal skin, the stratum granulosum/spinosum of psoriatic skin, and the secretory coils of eccrine sweat glands. Low expression levels are found in the nasal cavity. |
| 翻译后修饰 | Substrate for transglutaminases. Acts as an acyl acceptor but not as an acyl donor. |
| 相似性 | Belongs to the cystatin family. |
| 功能 | Shows moderate inhibition of cathepsin B but is not active against cathepsin C. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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Cystatin B Rabbit pAb, Cy3 conjugated(bs-5158R-Cy3)-100ul
￥2980
