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- Bioss
- bs-10144R-Cy7
- 2025年09月30日
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100ul
| 产品编号 | bs-10144R-Cy7 |
| 英文名称 | CD35 Rabbit pAb, Cy7 conjugated |
| 中文名称 | Cy7标记的Ⅰ型补体受体（C3b/C4b受体）抗体 |
| 英文别名 | C3 binding protein; C3b/C4b receptor; C3BR; C4BR; CD 35; CD35 antigen; complement component(3b/4b) receptor 1(Knops blood group); complement component(3b/4b) receptor 1 including Knops blood group system; Complement component receptor 1; Complement receptor 1; Complement receptor type 1; CR 1; CR1; CR1_HUMAN; KN; Knops blood group antigen. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CR1/CD35 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Cell Type Markers > CD > Myeloid Cells Stem Cells > Hematopoietic Progenitors > Myeloid > Dendritic Cell Lineage Stem Cells > Hematopoietic Progenitors > Myeloid > Neutrophil Lineage |
| 亚基 | Monomer. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Present on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. |
| 相似性 | Belongs to the receptors of complement activation (RCA) family. Contains 30 Sushi (CCP/SCR) domains. |
| 功能 | Mediates cellular binding of particles and immune complexes that have activated complement. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The genome is polymorphic at this locus with allele-specific splice variants encoding different isoforms, based on the presence/absence of long homologous repeats (LHRs). The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in this gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus, sarcoidosis and Alzheimer's disease. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. [provided by RefSeq, May 2020] |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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CD35 Rabbit pAb, Cy7 conjugated(bs-10144R-Cy7)-100ul
￥2980
