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- Bioss
- bs-13680R-PerCP-Cy7
- 2025年09月30日
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产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-13680R-PerCP-Cy7 |
| 英文名称 | UBXN2B Rabbit pAb, PerCP-Cy7 conjugated |
| 中文名称 | PerCP-Cy7标记的UBXN2B蛋白抗体 |
| 英文别名 | NSFL1 cofactor p37; p37; p97 cofactor p37; UBX domain containing protein 2B; UBX domain protein 2B; UBX domain-containing protein 2B; UBX2B_HUMAN; UBXN2B |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human UBXN2B |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Adapters > Cytoplasmic Signal Transduction > Protein Trafficking > ER Proteins Signal Transduction > Protein Trafficking > Golgi Proteins |
| 亚基 | Interacts with VCP. Does not bind ubiquitin (By similarity). |
| 亚细胞定位 | Nucleus. Cytoplasm; cytosol. Endoplasmic reticulum. Golgi apparatus. |
| 相似性 | Belongs to the NSFL1C family. _x000D_ Contains 1 SEP domain. _x000D_ Contains 1 UBX domain. |
| 功能 | Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The UBX (Ubiquitin regulatory X) domain is an 80 amino acid motif that is usually present on the carboxy-terminus of certain eukaryotic proteins. UBX domain-containing proteins (UBXD), such as FAF1, p33ING1 and D8S2298E, are typically involved in ubiquitin-related processes. UBXD proteins also constitute the largest family of VCP cofactors and are generally involved in substrate recruitment to VCP, as well as regulation of its activity. UBXD2B (UBX domain-containing protein 2B), also known as NSFL1 cofactor p37 and p97 cofactor p37, is a 331 amino acid protein that contains one UBX domain and one SEP domain. UBXN2B is required for ER and Golgi biogenesis and also plays a role in their maintenance during interphase, as well as their reassembly at the end of mitosis. Through interaction with VCP, UBXN2B forms a complex that has membrane fusion activity. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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UBXN2B Rabbit pAb, PerCP-Cy7 conjugated(bs-13680R-PerCP-Cy7)-100ul
￥2980
