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- bs-1082R-Cy5
- 2025年09月30日
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100ul
| 产品编号 | bs-1082R-Cy5 |
| 英文名称 | GRK1 Rabbit pAb, Cy5 conjugated |
| 中文名称 | Cy5标记的G蛋白偶合受体激酶1抗体 |
| 英文别名 | G-protein coupled receptor kinase 1; GRK1; GPRK1; RK; Grk1; Rhok; RHODOPSIN KINASE; RK_HUMAN. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GRK1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Neurotransmission > Intracellular Signaling > Kinases Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Neuroscience > Sensory System > Visual system Signal Transduction > Protein Phosphorylation > Tyrosine Kinases > Receptor Tyrosine Kinases |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Retina and pineal gland. |
| 翻译后修饰 | Autophosphorylated. _x000D_ Farnesylation is required for full activity. |
| 相似性 | Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family._x000D_
GPRK subfamily. _x000D_ Contains 1 AGC-kinase C-terminal domain. _x000D_ Contains 1 protein kinase domain. _x000D_ Contains 1 RGS domain. |
| 功能 | Phosphorylates rhodopsin thereby initiating its deactivation. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq] |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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GRK1 Rabbit pAb, Cy5 conjugated(bs-1082R-Cy5)-100ul
￥2980
