PHLP Rabbit pAb, BF405 conjugated(bs-5812R-BF405)-100ul

PHLP Rabbit pAb, BF405 conjuga

ted(bs-5812R-BF405)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-5812R-BF405
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-5812R-BF405
    英文名称PHLP Rabbit pAb, BF405 conjugated
    中文名称BF405标记的光导蛋白样蛋白PDCL抗体
    英文别名PDCL; Phosducin Like; PhLP; Phosducin-Like Protein; PHLOP1; Phosducin like protein; PhLP1; PHLP_HUMAN.
    产品应用IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human PHLP
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Forms a complex with the beta and gamma subunits of the GTP-binding protein, transducin.
    Interacts with the CCT chaperonin complex.
    组织特异性Expressed in buccal mucosa cell and 236 other tissues
    相似性Belongs to the phosducin family.
    功能Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
    Isoform 1:_x000D_ Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers.
    Isoform 2:_x000D_ Acts as a negative regulator of heterotrimeric G proteins assembly by trapping the preloaded G beta subunits inside the CCT chaperonin.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {IF}{1:100-500}

     

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