Msx2 Rabbit pAb, APC-Cy7 conjugated(bs-10158R-APC-Cy7)-100ul

Msx2 Rabbit pAb, APC-Cy7 conju

gated(bs-10158R-APC-Cy7)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-10158R-APC-Cy7
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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      产品信息以Bioss网站为准

    • 规格：

      100ul

    产品编号bs-10158R-APC-Cy7
    英文名称Msx2 Rabbit pAb, APC-Cy7 conjugated
    中文名称APC-Cy7标记的同源盒基因Msx2抗体
    英文别名Msx2/Hox8; CRS 2; CRS2; FPP; Homeo box msh like 2; Homeobox protein Hox-8; Homeobox protein MSX 2; Homeobox protein MSX-2; Homeobox protein MSX2; Hox 8; Hox8; MSH; Msh homeo box 2; Msh homeo box homolog; Msh homeo box homolog 2; Msh homeobox 2; Msh homeobox homolog 2; Msx 2; Msx2; MSX2_HUMAN; Parietal foramina 1; PFM 1; PFM; PFM1.
    产品应用ICC/IF=1:50-200, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Msx2/Hox8
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Signal transduction

    Cardiovascular > Heart > Cardiogenesis > Transcription factors/regulators

    Epigenetics and Nuclear Signaling > Transcription > Other factors

    Neuroscience > Neurology process > Neurogenesis

    亚基Interacts with MINT. Interacts with XRCC6 (Ku70) and XRCC5 (Ku80).
    亚细胞定位Nucleus.
    相似性Belongs to the Msh homeobox family.
    Contains 1 homeobox DNA-binding domain.
    功能Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq, Jul 2008].

     

    应用推荐稀释比例
    {ICC/IF}{1:50-200}
    {IF}{1:100-500}

     

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