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- bsm-0957M-IRDye800CW
- 2025年09月30日
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100ul
| 产品编号 | bsm-0957M-IRDye800CW |
| 英文名称 | PAG608 (3E4) Mouse mAb, IRDye 800CW conjugated |
| 中文名称 | IRDye 800CW标记的野生型P53诱导基因1单克隆抗体 |
| 英文别名 | p53 activated gene 608; PAG608; FLJ12296; MGC10613; OTTHUMP00000211906; OTTHUMP00000211907; p53-activated gene 608 protein; PAG 608; WIG 1; Zinc finger matrin-type protein 3; Zinc finger protein WIG-1; ZMAT3_HUMAN; p53 inducible zinc finger protein; p53 target zinc finger protein; PAG 608; WIG 1; WIG 1/PAG608 protein; WIG1; WIG1/PAG608 protein; Zinc finger matrin type 3; Zinc finger protein WIG 1; Zinc finger protein WIG1; ZMAT 3; ZMAT3. |
| 产品应用 | WB=1000-10000 Not yet tested in other applications. |
| 抗体来源 | Mouse |
| 免疫原 | KLH conjugated synthetic peptide derived from human WIG-1/PAG608 |
| 亚型 | IgG1 |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Monoclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cell Death > Apoptosis > Metabolism Cell Biology > Apoptosis > Intracellular > p53 Pathway Epigenetics and Nuclear Signaling > Cell cycle > Apoptosis > Nuclear Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger Metabolism > Pathways and Processes > Metabolism processes > Apoptosis |
| 亚基 | Interacts with dsRNA. |
| 亚细胞定位 | Nucleus. Nucleus, nucleolus. |
| 组织特异性 | Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine. |
| 相似性 | Contains 3 matrin-type zinc fingers. |
| 功能 | Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid. |
| 应用 | 推荐稀释比例 |
| {WB} | {1000-10000} |
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PAG608 (3E4) Mouse mAb, IRDye 800CW conjugated(bsm-0957M-IRDye800CW)-100ul
￥2980
