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- Bioss
- bs-5945R-RBITC
- 2025年09月30日
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100ul
| 产品编号 | bs-5945R-RBITC |
| 英文名称 | SnoN Rabbit pAb, RBITC conjugated |
| 中文名称 | RBITC标记的Smad核转录共抑制因子抗体 |
| 英文别名 | SKI like; Ski related oncogene; Ski related protein; SKIL; SnoA; SNO; SnoA; SnoI; SnoN; SKIL_HUMAN. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human SnoN |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Oncoproteins/suppressors > Oncoproteins Cancer > Oncoproteins/suppressors > Tumor suppressors Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > SMADs |
| 亚基 | Interacts with SMAD2, SMAD3 and RNF111. Isoform 1 interacts with WWP1. |
| 组织特异性 | Isoform SNON and isoform SNOA are widely expressed. Highest expression is found in skeletal muscle, followed by placenta and lung. Lowest expression in heart, brain and pancreas. Isoform SNOI expression is restricted to skeletal muscle. |
| 相似性 | Belongs to the SKI family. |
| 功能 | May have regulatory role in cell division or differentiation in response to extracellular signals. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | SnoN may have a regulatory role in cell division or differentiation in response to extracellular signals. SnoN acts as a positive mediator of TGF beta induced transcription and cell cycle arrest in lung epithelial cells. The ability of SnoN to repress the growth inhibitory function of the Smad proteins is required for their transforming activity. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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SnoN Rabbit pAb, RBITC conjugated(bs-5945R-RBITC)-100ul
￥2980
