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- Bioss
- bs-18947R-HRP
- 2025年09月30日
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100ul
| 产品编号 | bs-18947R-HRP |
| 英文名称 | MITD1 Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的MITD1蛋白抗体 |
| 英文别名 | Microtubule interacting and transport domain containing 1; MIT; MIT domain containing protein 1; MIT microtubule interacting and transport domain containing 1; MITD 1. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MITD1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Homodimer. Interacts (via MIT domain) with CHMP1A, CHMP1B, CHMP2A and IST1. |
| 亚细胞定位 | Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Midbody. Membrane; Peripheral membrane protein; Cytoplasmic side. |
| 相似性 | Contains 1 MIT domain. |
| 功能 | Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | MITD1 is a 249 amino acid peripheral membrane protein that localizes to the cytoplasmic side of late endosomes, where it is Implicated in endosomal protein transport. MITD1 interacts with CHMP2 and CHMP1B, and is encoded by a gene that maps to human chromosome 2q11.2. As the second largest human chromosome, chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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MITD1 Rabbit pAb, HRP conjugated(bs-18947R-HRP)-100ul
￥2980
