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- Bioss
- bs-5786R-BF700
- 2025年09月30日
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100ul
| 产品编号 | bs-5786R-BF700 |
| 英文名称 | KLST/Kallistatin Rabbit pAb, BF700 conjugated |
| 中文名称 | BF700标记的激肽释放酶抑制剂抗体 |
| 英文别名 | Serpin peptidase inhibitor clade A member 4; Kallikrein binding protein; Kallikrein inhibitor; Protease inhibitor 4; Serpin A4; KAL; Kallikrein binding protein; Kallikrein inhibitor; KBP; KLST; KST; MGC108582; PI4; Protease inhibitor 4; Serpin A4; Serpin peptidase inhibitor clade A member 4; SERPINA4; KAIN_HUMAN. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human KLST/Kallistatin |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Invasion/microenvironment > Angiogenesis > Angiogenic inhibitory factors Cardiovascular > Angiogenesis > Inhibitors Cardiovascular > Blood > Serum Proteins Cell Biology > Proteolysis / Ubiquitin > Protease inhibitors > Serine protease inhibitors > SERPINs |
| 亚基 | Monomer and some homodimers. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed by the liver and secreted in plasma. |
| 翻译后修饰 | The N-terminus is blocked. |
| 相似性 | Belongs to the serpin family. |
| 功能 | Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Kallistatin is a serine proteinase inhibitor which binds to tissue kallikrein and inhibits its amidolytic and kininogenase activity. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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KLST/Kallistatin Rabbit pAb, BF700 conjugated(bs-5786R-BF700)-100ul
￥2980
