CDCA7L Rabbit pAb, Pacific Blue conjugated(bs-5963R-PacificBlue)-100ul

CDCA7L Rabbit pAb, Pacific Blu

e conjugated(bs-5963R-PacificBlue)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-5963R-PacificBlue
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-5963R-PacificBlue
    英文名称CDCA7L Rabbit pAb, Pacific Blue conjugated
    中文名称Pacific Blue标记的细胞分裂周期相关蛋白JPO2抗体
    英文别名c Myc Interacting protein JPO2; DKFZp762L0311; RAM2; HR1; JPO2; Protein JPO2; R1 antibody Transcription Factor RAM2.CDA7L_HUMAN
    产品应用IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CDCA7L
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Oncoproteins/suppressors > Oncoproteins > Transcription factors

    Cell Biology > Apoptosis > Intracellular > Associated Proteins

    Epigenetics and Nuclear Signaling > Transcription > Other factors

    Epigenetics and Nuclear Signaling > Transcription > Transcription Factors

    亚基Interacts with MYC and PSIP1.
    亚细胞定位Cytoplasm. Nucleus. Note=Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.
    组织特异性Ubiquitous. Overexpressed in medulloblastoma.
    功能Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料CDCA7L is a member of the CDCA (cell division cycle associated) protein family. Members of this family have expression patterns associated with other known cell cycle genes such as cyclins and CDC genes. CDCA7L plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. It also plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. It is involved in apoptotic signaling pathways and may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

     

    应用推荐稀释比例
    {IF}{1:100-500}

     

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