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- Bioss
- bs-5940R-BF594
- 2025年09月30日
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100ul
| 产品编号 | bs-5940R-BF594 |
| 英文名称 | RAD54B Rabbit pAb, BF594 conjugated |
| 中文名称 | BF594标记的DNA修复和重组蛋白RAD54B抗体 |
| 英文别名 | DNA repair and recombination protein RAD54B; Fibrinogen silencer binding protein; FSBP; RAD54 homolog B; RA54B_HUMAN. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human RAD54B |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Interacts with RAD51 through the NH2-terminal domain. Immunoprecipitation experiments show that the interaction is constitutive and not induced by ionizing radiation. The interaction may be indirect. |
| 亚细胞定位 | Nucleus (Probable). |
| 组织特异性 | Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon. |
| 相似性 | Belongs to the SNF2/RAD54 helicase family. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain._x000D_ |
| 功能 | Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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RAD54B Rabbit pAb, BF594 conjugated(bs-5940R-BF594)-100ul
￥2980
