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- bsm-0388M-BF405
- 2025年09月30日
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100ul
| 产品编号 | bsm-0388M-BF405 |
| 英文名称 | IFN gamma(F2E4) Mouse mAb, BF405 conjugated |
| 中文名称 | BF405标记的γ-干扰素/γ-IFN单克隆抗体 |
| 英文别名 | IFNG; IFG; IFI; IFN gamma; IFN Immune; IFN-gamma; IFNG; IFNG_HUMAN; Immune Interferon; Interferon gamma; Interferon gamma Precursor; Macrophage Activating Factor; MAF; T Cell Interferon; Type II Interferon; hIFN-gamma. |
| 产品应用 | Flow-Cyt=1ug/Test, ICC/IF=1:50-200 Not yet tested in other applications. |
| 抗体来源 | Mouse |
| 免疫原 | Recombinant Full length of human IFN gamma |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Tumor immunology > Cytokines > Interferons Immunology > Adaptive Immunity > Regulatory T Cells Immunology > Innate Immunity > Cytokines > Interferons Stem Cells > Signaling Pathways > TGF beta > Interferon gamma |
| 亚基 | Homodimer. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Released primarily from activated T lymphocytes. |
| 翻译后修饰 | Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161. |
| 相似性 | Belongs to the type II (or gamma) interferon family. |
| 功能 | Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Mammalian Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1ug/Test} |
| {ICC/IF} | {1:50-200} |
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IFN gamma(F2E4) Mouse mAb, BF405 conjugated(bsm-0388M-BF405)-100ul
￥2980
