MPRIP Rabbit pAb, PE-Cy5.5 conjugated(bs-13672R-PE-Cy5.5)-100ul

MPRIP Rabbit pAb, PE-Cy5.5 con

jugated(bs-13672R-PE-Cy5.5)-100ul
收藏
  • ￥2980
  • Bioss已认证
  • bs-13672R-PE-Cy5.5
  • 2025年09月30日
  • 产品信息以Bioss网站为准
avatar
北京博奥森生物技术有限公司
品牌商
9 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 技术资料
    • 应用范围：

      产品信息以Bioss网站为准

    • 规格：

      100ul

    产品编号bs-13672R-PE-Cy5.5
    英文名称MPRIP Rabbit pAb, PE-Cy5.5 conjugated
    中文名称PE-Cy5.5标记的MPRIP蛋白抗体
    英文别名9530046C02; AA536749; AI647711; C76423; KIAA0864; M-RIP; MGC67316; mKIAA0864; Mprip; MPRIP_HUMAN; Myosin phosphatase Rho-interacting protein; p116 Rho-interacting protein; p116Rip; Rho-interacting protein 3; Rhoip3; RIP3; RP23-180B18.4.
    产品应用ICC/IF=1:50-200, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human MPRIP
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin Assembly

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin Binding Proteins

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Myosin

    亚基Binds F-actin through its N-terminus. Interacts with MYZAP. Binds RHOA, PPP1R12A/MBS and PPP1R12C/MBS85 through adjacent coiled coil domains.
    亚细胞定位Cytoplasm; cytoskeleton. Colocalizes with F-actin.
    相似性Contains 2 PH domains.
    功能Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料M-RIP is a 1,025 amino acid cytoplasmic and cytoskeletal protein that is required for regulation of the actin cytoskeleton. M-RIP colocalizes with myosin binding subunit (MBS) to regulate the phosphorylation of myosin light chain, and colocalizes with F-actin through its N-terminus in the cytoskeleton. M-RIP also interacts with and RhoA at actin stress fibers via its adjacent coiled coil domains. M-RIP is highly expressed in ovary, with moderate levels found in brain, heart, liver, lung, skeletal muscle, testis and kidney. M-RIP depletion causes an increase of stress fibers in smooth muscle cells, whereas M-RIP over-expression causes disassembly of stress fibers in neuronal cells. Containing two PH domains, M-RIP has multiple phosphorylated serine and threonine residues and exists as three isoforms which are produced by alternative splicing events.

     

    应用推荐稀释比例
    {ICC/IF}{1:50-200}
    {IF}{1:100-500}

     

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    IgG (Mouse) Isotype Control (R-PE/Cy5.5)
    $256
    上海瑶韵生物科技有限公司
    2025年07月12日询价
    bs-0293P-Cy5
    ￥780
    上海晶风生物科技有限公司
    2025年06月25日询价
    MPRIP antibody (PE),orb490606,biorbyt
    ￥4400
    武汉博欧特生物科技有限公司
    2025年03月03日询价
    Rabbit anti-MPRIP/M-RIP Antibody, Affinity Purified; MPRIP/M-RIP抗体
    询价
    上海优宁维生物科技股份有限公司
    2025年07月13日询价
    Rabbit IgG / PE-Cy5抗体
    ￥1080
    上海谷研实业有限公司
    2025年05月23日询价
    MPRIP Rabbit pAb, PE-Cy5.5 conjugated(bs-13672R-PE-Cy5.5)-100ul
    ￥2980