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- bs-2550R-Cy3
- 2025年09月30日
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100ul
| 产品编号 | bs-2550R-Cy3 |
| 英文名称 | NAP2 Rabbit pAb, Cy3 conjugated |
| 中文名称 | Cy3标记的中性粒细胞活性蛋白2/血小板碱性蛋白抗体 |
| 英文别名 | B TG1; beta TG; b-TG1; beta-TG; NAP-2; NAP2; NAP 2; beta thromboglobulin; Chemokine(C X C motif) ligand 7; Connective tissue activating peptide III; CTAP 3; CTAP III; CTAP3; CTAPIII; CXC chemokine ligand 7; CXCL 7; CXCL7; LA PF 4; LA-PF4; LDGF; Leukocyte derived growth factor; Low affinity platelet factor IV; MDGF; NAP 2; NAP-2; NAP 2 L1; Neutrophil activating peptide 2; PBP; Platelet basic protein; Platelet basic protein precursor; PPBP; Pro platelet basic protein; SCYB7; Small inducible cytokine B7; Small inducible cytokine subfamily B member 7; TC1; TC2; TGB; TGB1; THBGB; THBGB1; Thrombocidin 1; Thrombocidin 2; Thromboglobulin beta 1. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from mouse CXCL7 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Beta-thromboglobulin is a homotetramer. |
| 亚细胞定位 | Secreted. |
| 翻译后修饰 | Proteolytic removal of residues 1-9 produces the active peptide connective tissue-activating peptide III (CTAP-III) (low-affinity platelet factor IV (LA-PF4)). _x000D_ Proteolytic removal of residues 1-13 produces the active peptide beta-thromboglobulin, which is released from platelets along with platelet factor 4 and platelet-derived growth factor. _x000D_ NAP-2(1-66) is produced by proteolytical processing, probably after secretion by leukocytes other than neutrophils. _x000D_ NAP-2(73) and NAP-2(74) seem not be produced by proteolytical processing of secreted precursors but are released in an active form from platelets. |
| 相似性 | Belongs to the intercrine alpha (chemokine CxC) family. |
| 功能 | LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. [provided by RefSeq, May 2010]. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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NAP2 Rabbit pAb, Cy3 conjugated(bs-2550R-Cy3)-100ul
￥2980
