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- bs-17766R-BF680
- 2025年09月30日
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100ul
| 产品编号 | bs-17766R-BF680 |
| 英文名称 | MRP6 Rabbit pAb, BF680 conjugated |
| 中文名称 | BF680标记的多药耐药相关蛋白6抗体 |
| 英文别名 | ABC34; Abcc6; Anthracycline resistance-associated protein; ARA; ATP binding cassette sub family C(CFTR/MRP) member 6; ATP binding cassette sub family C member 6; ATP-binding cassette sub-family C member 6; EST349056; MLP1; MOAT E; MOAT-E; MOATE; MRP 6; MRP6; MRP6_HUMAN; Multi-specific organic anion transporter E; Multidrug resistance associated protein 6; Multidrug resistance-associated protein 6; multispecific organic anion transporter E; PXE; PXE1; URG7; URG7 protein. |
| 产品应用 | ICC/IF=1:50-200, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MRP6 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism Signal Transduction > Metabolism > Drug metabolism Signal Transduction > Metabolism > Plasma Membrane > Channels |
| 亚细胞定位 | Membrane. Localized to the basolateral membrane. |
| 组织特异性 | Expressed in kidney and liver. Very low expression in other tissues. |
| 相似性 | Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. _x000D_ Contains 2 ABC transmembrane type-1 domains. _x000D_ Contains 2 ABC transporter domains. |
| 功能 | May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Transports glutathione conjugates as leukotriene-c4 (LTC4) and N-ethylmaleimide S-glutathione (NEM-GS). |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {ICC/IF} | {1:50-200} |
| {IF} | {1:100-500} |
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MRP6 Rabbit pAb, BF680 conjugated(bs-17766R-BF680)-100ul
￥2980
