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- bs-0556R-APC-Cy7
- 2025年09月30日
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100ul
| 产品编号 | bs-0556R-APC-Cy7 |
| 英文名称 | HMGA2 Rabbit pAb, APC-Cy7 conjugated |
| 中文名称 | APC-Cy7标记的高迁移率族蛋白A2抗体 |
| 英文别名 | HMGA 2; BABL; High mobility group(nonhistone chromosomal) protein isoform I C; High mobility group(nonhistone chromosomal) protein isoform IC; High Mobility Group AT hook 2; High Mobility Group AT hook protein 2; High mobility group protein HMGI C; High mobility group protein HMGIC; High mobility group protein I, isoform C; HMGA 2; HMGI C; HMGIC; LIPO; Non histone chromosomal architectural protein HMGI C; Non histone chromosomal architectural protein HMGIC; Pygmy; STQTL9; HMGA2_HUMAN. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human HMGA2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cell cycle > Cell differentiation Developmental Biology > Post embryonic development > Aging Epigenetics and Nuclear Signaling > Cell cycle > Cell Differentiation Epigenetics and Nuclear Signaling > Histones > HMGs Neuroscience > Cell Type Marker > Neural Stem Cell marker Neuroscience > Neurology process > Metabolism Neuroscience > Neurology process > Neurogenesis Stem Cells > Neural Stem Cells > Intracellular |
| 亚基 | Interacts with E4F1. Interacts with NEK2 (By similarity). |
| 亚细胞定位 | Nucleus. |
| 翻译后修饰 | Regulated by cell cycle-dependent phosphorylation which alters its DNA binding affinity. Phosphorylated by NEK2. |
| 相似性 | Belongs to the HMGA family._x000D_
Contains 3 A.T hook DNA-binding domains. |
| 功能 | Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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HMGA2 Rabbit pAb, APC-Cy7 conjugated(bs-0556R-APC-Cy7)-100ul
￥2980
